Former Ferrari driver Massa lost that title by a point to Lewis Hamilton, now at Mercedes and a seven-time world champion.
The Brazilian, 42, says an alleged "conspiracy" denied him the title because the sport's leaders knew the 2008 Singapore Grand Prix was manipulated but took no action until a year later.
Wolff suggested that outcome could also be challenged if Massa were to succeed with his case.
"The FIA commented on the 2021 race with a clear statement so that's why we are looking at it with interest," he said.
The governing FIA said in March 2022 after an enquiry that "the results of the 2021 Abu Dhabi Grand Prix and the FIA Formula One World Championship are valid, final and cannot now be changed."
Persons:
Felipe Massa, Edgar Su, Felipe Massa's, Toto Wolff, Massa, Lewis Hamilton, Nelson Piquet, Fernando Alonso, Wolff, Hamilton, Max Verstappen, Michael Masi . Wolff, Alan Baldwin, Ken Ferris
Organizations:
Singapore, Circuit, Rights, Ferrari, Mercedes, Renault, FIA, Abu, Prix, Thomson
Locations:
Singapore, Rights SINGAPORE, Abu Dhabi, London